About 4 results found for searched term "BMS-8 " (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28672 | BMS-986118 | GPR/FFAR |
| BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models. | ||
| M28797 | BMS-8 | PD-1/PD-L1 |
| BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1. | ||
| M28848 | BMS-986188 | Opioid Receptor |
| BMS-986188 is a selective positive allosteric modulator of δ-opioid receptor with an EC50 of 0.05 μM. | ||
| M30378 | BMS-585248 | HIV Protease |
| BMS-585248 is a potent, third-generation HIV-1 attachment inhibitor with a promising initial in vitro and in vivo pharmacokinetic profile. | ||
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